Metabolic Xtra 90’s

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Verifiable Science

Metabolic Xtra provides a combination of nutrients to support healthy glucose metabolism and insulin receptor function and signaling. The natural plant alkaloid berberine enhances the expression and function of insulin receptors.^1,2 In a randomized, placebo-controlled trial involving 116 subjects, berberine provided statistically significant support for healthy glucose and lipid metabolism.³ Resveratrol has been shown to support cellular metabolism and glucose homeostasis by promoting healthy AMPK and SIRT1 protein levels.^4,5 The trace mineral chromium plays an important role in glucose and lipid metabolism, as well as enzyme activation.^6,7 Alpha lipoic acid provides support for healthy insulin receptor function and glucose metabolism.^8,9

References

1. Zhang H, et al. Metabolism. 2010 Feb;59(2):285-92.
2. Yan-xia N, et al. Chin J Integr Med. 1995; 1(2); 91-95.
3. Zhang Y, et al. J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65.
4. Timmers S, et al. Cell Metab. 2011 Nov 2;14(5):612-22.
5. Crandall JP, et al. J Gerontol A Biol Sci Med Sci. 2012 Dec;67(12):1307-12.
6. Frauchiger MT, et al. J Am Coll Nutr. 2004 Aug;23(4):351-7.
7. Rabinovitz H, et al. Int J Vitam Nutr Res. 2004 May;74(3):178-82.
8. Jacob S, et al. Free Radic Biol Med. 1999 Aug;27(3-4):309-14.
9. Ansar H, et al. Saudi Med J. 2011 Jun;32(6):584-8.

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