The lipotropic agents choline, betaine, methionine, vitamin B6, vitamin B12 and folic acid support healthy hepatic fat metabolism and bile flow. Efficient processing and breakdown of fats in the liver maintains healthy overall liver function and detoxification. As methyl donors, these same nutrients are also critical for methylation, a widespread biochemical process in the body that involves transferring a methyl group to another compound. Methylation of DNA supports healthy DNA integrity and stability, important for liver, colon and overall cell health. These nutritional factors are also highly recognized for their ability to maintain healthy homocysteine metabolism. Taurine, curcumin, silymarin and artichoke have been added for their abilities to support healthy bile flow, gene expression and the body’s normal toxin metabolism.